HistoCore NANOCUT R - Automated Research & Special Applications Rotary Microtome
14052458261
Discover New Breakthroughs with an Enhanced Level of Precision and Versatility
When your microtomy involves diverse samples in order to discover new breakthroughs in your research projects, then NANOCUT R is the optimal solution for you. The new generation of microtomes from Leica Biosystems is built upon our 145+ year heritage of market-leading microtome design. From biomedical research to industrial applications, NANOCUT R can cut virtually anything you put in front of it.
- Cut sections that can be prepared for analysis in light microscopy and electron microscopy - down to 250nm (0.25µm, semi-thin).
- Preserve sample integrity when performing semi-thin sectioning with the Special Spindle and expanded Slow Speed Adjustment.
- Precisely stop the sample in the object head’s optimal position for photo-capture of the cut sample surface when running 3-dimensional reconstruction programs.*
*Source for Featured 3D Reconstruction Content: IGBMC, PHENOMIN, iCS
Specs
Product Specifications
General
| Type: | Motorized |
| Nominal Supply Voltage: | 100 / 120 / 230 / 240 V AC |
| Nominal Frequency: | 50/60 Hz |
| Maximum Power Consumption: | 100 VA |
| Protection Class: | I |
| Power Fuses: | 2 x T3,15 AL, 250V |
| Pollution Degree: | 2 |
| Overvoltage Category: | II |
| Maximum Heat Emission: | 340 J/s |
| Operating Temperature Range: | +18°C to +35°C |
| Temperature Range During Storage: | +5°C to +50°C |
| Relative Humidity During Operation: | 20% to Max. 80% Non-Condensing |
| Relative Humidity During Storage: | 10% to Max. 85% Non-Condensing |
Dimensions & Weight
| BASIC INSTRUMENT | |
|---|---|
| Width (including handwheel): | 415 mm |
| Depth (including waste tray): | 620 mm |
| Height (without top tray): | 295 mm |
| Weight (without accessories): | Approx. 40 kg |
| CONTROL PANEL | |
|---|---|
| Type: | Separate control panel & in-housing integrated instrument control panel |
| Width: | 119 mm |
| Depth: | 193 mm |
| Height: | 50 mm |
| Height (in inclined position): | 81 mm |
| Weight (net): | 0.6 kg |
Microtome Performance Specs
| Specimen Feed: | approx. 24 mm ±1 mm |
| Vertical Stroke: | 70 mm ±1 mm |
| Large Standard Clamp: 55 x 50 x 30 mm Super Cassette Clamp: 68 x 48 x 15 mm | |
| Motorized Sectioning Speeds: | 0 - 195 mm/s ±10% |
| SPECIMEN RETRACTION | |
|---|---|
| In Manual Sectioning Mode: | 5 - 50 µm (in 5 µm increments); can be turned off |
| In Motorized Sectioning Mode: | Speed-Dependent; can be turned off |
| SPECIMEN ORIENTATION | |
|---|---|
| Horizontal: | ± 8° |
| Vertical: | ± 8° |
| SECTION THICKNESS SETTINGS | |
|---|---|
| Range: | 0.25 - 50 µm |
| Setting Values: | 0.25 - 0.5 µm (in 0.25 µm increments) |
| 0.5 - 5 µm (in 0.5 µm increments) | |
| 5 - 20 µm (in 1 µm increments) | |
| 20 - 50 µm (in 5 µm increments) |
| TRIMMING SECTION THICKNESS SETTINGS: | |
|---|---|
| Range: | 1 - 300 µm |
| Setting Values: | 1 - 10 µm (in 1 µm increments) |
| 10 - 20 µm (in 2 µm increments) | |
| 20 - 50 µm (in 5 µm increments) | |
| 50 - 100 µm (in 10 µm increments) | |
| 100 - 300 µm (in 50 µm increments) |
Additional Specifications
| Handwheel Balance System: | |
| Handwheel Lock / Brake: | 2 Mechanical Locks, 1 Electronic Brake |
| Safety Hand Wheel: | Handle can be Centered |
| WASTE TRAY | |
|---|---|
| Type | Standard Waste Tray |
| Waste Tray Volume | 1400 ml |
| SELECTABLE CUTTING MODES | |
|---|---|
| Rock Mode: | - with activated retraction |
| Single Mode: | |
| Continuous Mode: | |
| Step Mode: | |
| Program Mode: |
| BLADE HOLDER | |
|---|---|
| Type: | Semi-Thin Sectioning - Knife Holder GD Resin Sectioning - Knife Holder NZ or Knife Holder E-TC Paraffin Sectioning: 2-in-1 Blade Holder E |
| North-South Movement: | ± 24 mm |
| East-West Movement: | 3 Positions |
| Lateral Displacement Function: | via knife holder CE clamping top |
| SPECIAL FEATURES | |
|---|---|
| Remaining Feed Indicator | Visual and Acoustical |
| Section Counter | |
| Section Thickness Totalizer | |
| Memory Position | |
| Special Spindle for Precise Semi-Thin Sectioning | |
| Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning | |
| Precise 3D Object Head Stop Position |
Features
Product Features
Precise and Consistent Semi-Thin Sectioning
Avoid destruction of samples with the Special Spindle and expanded Slow Speed Adjustment capabilities which allow you to produce consistent semi-thin sections down to 250nm.
Tackle the Toughest Materials with a Wide Range of Accessories
Leverage a wide range of accessories available to the NANOCUT R, including holders for disposable steel and tungsten carbide blades, reusable knives, and a special holder for glass and diamond knives.
3D Reconstruction Stacking Technique
Precisely stop the sample in the object head's optimal position for photo-capture of the cut sample surface when running 3-dimensional reconstruction programs.
Precision-Orientation System
Always get back to a 0-position home on the microtome, regardless of how you (or another tech) have changed the instrument's orientation.
Force Balance System
Minimize the risk of injury to the operator or specimen by an unbalanced object head.
Compare
Quick Compare Chart
Product |
HistoCore BIOCUT R |
 HistoCore MULTICUT R |
HistoCore AUTOCUT R |
 HistoCore NANOCUT R Currently viewing |
| Type | Mechanical | Semi-Motorized | Motorized | Motorized |
| Precision-Orientation System | ||||
| Force Balance System | ||||
| 2-in-1 Blade Holder | ||||
| Specimen Cooling Option with RM CoolClamp | ||||
| Standard Waste Tray | ||||
| Silent Retraction | ||||
| Personalized Coarse Feed Wheel | ||||
| Fast Homing | ||||
| Memory Position | ||||
| Electronic Brake | ||||
| Special Spindle for Precise Semi-Thin Sectioning | ||||
| Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning | ||||
| Precise 3D Object Head Stop Position |
Documents
Documents
Brochure
Certificates
| EC Declaration HistoCore NANOCUT R A en | (PDF) |
IFUs
White Paper
| 18700 Rev A White Paper HistoCore NANOCUT R High Resolution Episcopic Microscopy | (PDF) |
Resources
Resources
Product Feature Demo Videos
Force Balance System
Electronic Brake
Nanocut R instrument
Frequently Asked Questions
HistoCore Microtomes
Does the new HistoCore RM antistatic tray fit on the older RM22xx series?
No – the microtome base plates of both series have different dimensions and are not compatible with each other.
How does the new antistatic waste tray reduce contamination?
The antistatic waste tray is made from resistant antistatic material to avoid debris sticking to the walls of the tray.
Is the new 2-in-1 blade holder compatible as a whole assembly with the older RM22xx series?
Yes – only in the combination blade holder and 2-in-1 blade holder.
Can we still use the backlighting with the new blade holder base for the 2-in-1 blade holder?
No – the 2-in-1 blade holder base does not have the cut-out for the backlighting.
Which accessories of the older RM22xx Series cannot be used with the HistoCore RMs anymore?
- Small section waste tray
- Large section waste tray
- Top tray – HistoCore RM top tray is 40% larger than the RM22xx series tray
- Cooling Device – too small to be placed on instrument top. However, it’s still good to place next to the instrument
What is the advantage of the personalized coarse feed wheel?
Convenience and ease-of-user – users can select their personal preference of coarse feed wheel turn direction. This feature is preserved from the RM22xx series, allowing users to trim at the high pace.
What is the advantage of “Fast homing”?
The return speed of the object head from front to home position has been reduced from 26 seconds (older series) to 13 seconds (new series). This accelerated speed helps to shorten the sectioning process each time the object head is returned to home position.
What is the advantage of the Memory Position?
When batch trimming and using the same height of blocks, Memory Position will help to accelerate the sectioning.
- First insert a new block
- Bring the block to the blade
- Set the Memo position (stored)
- Trim
- Remove block for re-cooling
- Press “Memo” – the object head returns to the set object change position
- Insert a new block – check position
- Trim again
Configurations
Configurations
Choose your option below, and then use the Contact Us link above to submit a quote request for your selection
Basic Instrument (14052458261)
- Rotary microtome with Automated and Manual Modes
- Automatic Electronic Brake
- Special Spindle and expanded slow speed adjustment capabilities allows accurate specimen feeding for semi-thin sections of 250 nm
- Precise 3D object head stop position allows for taking pictures of the cut specimen surface after each section to enable 3D reconstruction
- Includes standard waste tray and top tray
